Clotz ACT Machine Cath Lab CTVS Cardiac Surgery CCU PTCA Heparin Dialysis Make in India | ACT Machine
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Heparin

Heparin is a naturally occurring polysaccharide. When it binds with antithrombin, a protein within blood, the heparin antithrombin complex alters many clotting factors and reactions. Unfractionated heparin is the most commonly used anticoagulant during Cardiac Surgeries (CTVS) like CABG, Cardiopulmonary bypass surgeries & Heart Valve Surgeries. It is also used in Cath Lab for Interventional Procedures like PTCA (Angiioplasty), Angiography, etc and in Intensive Care Units (ICU & CCU) or Renal Dialysis, etc.

heparin

Heparin Effects on Coagulation

Heparin affects the clot formation process in multiple ways. Significant effects on clot development are: higher heparin concentrations prolong the Coagulation Reaction Phase, increasing the ACT (Activated Clotting Time) result, and prolong the Clot Formation Phase.

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Act versus heparin

Heparin Management Objectives

Proper dosing of heparin during treatment improves patient outcomes since under administration elevates the risk of forming unwanted blood clots, and over-administration elevates the risk of bleeding. Heparin is metabolized. In order to maintain desired therapeutic heparin concentrations, heparin must be re-administrated periodically during CTVS surgery or Cath Lab Procedures or ICU / CCU or Renal Dialysis, etc. Accurate heparin dosing requires heparin monitoring to guide heparin re-administration.